Tag: wgbs
WGBS Pipeline: FASTQ to Methylation Calling
This skill executes the full ENCODE WGBS pipeline, processing paired-end FASTQ reads through alignment, deduplication, and methylation extraction. It generates per-CpG methylation levels in the standardized bedMethyl format, suitable for do…
Aggregate DNA Methylation Data Across Studies
Construct comprehensive tissue-level DNA methylation landscapes by aggregating WGBS data from multiple ENCODE experiments. The process includes quality-gating, coverage filtering, and the identification of hypomethylated regions and partial…
WGBS Pipeline: FASTQ to Methylation Calling
Executes the full ENCODE Whole Genome Bisulfite Sequencing pipeline, processing paired-end FASTQ files through alignment, deduplication, and methylation extraction. It generates comprehensive per-CpG methylation levels in the standard bedMe…
Aggregate DNA Methylation Across ENCODE Studies
Build comprehensive tissue-level DNA methylation landscapes by aggregating WGBS data from multiple ENCODE experiments. The skill handles quality-gating, coverage filtering, and the identification of hypomethylated regions and partially meth…