Tag: genomics
Annotate ENCODE Variants with ClinVar Data
This tool facilitates the cross-referencing of ENCODE functional genomic elements with ClinVar variant classifications. It supports both forward analysis (identifying variants within peaks) and reverse analysis (using ENCODE context to expl…
Resolving ENCODE Bulk Signals with CellxGene
This skill enables the integration of CellxGene Census single-cell RNA-seq data with bulk ENCODE functional genomics experiments to resolve cell-type-specific regulatory activity. It facilitates the deconvolution of bulk signals and the val…
Systematic ENCODE Experiment Batch Processing
Facilitates systematic batch operations across multiple ENCODE experiments, including quality control screening, bulk downloading, and comparative analysis. It provides workflows for managing large-scale data collections and generating summ…
Aggregate Chromatin Accessibility Peaks Across Studies
This skill generates a comprehensive union map of open chromatin by merging ATAC-seq and DNase-seq narrowPeak data from multiple ENCODE experiments. It handles cross-platform variation and applies rigorous filtering and confidence annotatio…